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Systemic vasculitis also known as systemic vasculitides, refers to a group of rare autoimmune disorders characterized by inflammation of the blood vessels (vasculitis) throughout the body. In these conditions, the immune system mistakenly attacks the blood vessels, causing inflammation, damage, and a wide range of symptoms, which can affect various organ systems. Systemic vasculitis can be a serious and potentially life-threatening condition if not properly managed.
There are multiple types of systemic vasculitis, each named based on the size and type of blood vessels primarily affected. Some common types of systemic vasculitis include:
1. Giant Cell Arteritis (GCA): GCA primarily affects large and medium-sized arteries, often in the head, neck, and upper body. It is most commonly seen in older adults and can lead to complications such as blindness if not treated promptly.
2. Takayasu Arteritis: This type primarily affects the aorta and its major branches, which can lead to narrowing and reduced blood flow to various organs.
3. Granulomatosis with Polyangiitis (GPA, formerly Wegener’s granulomatosis): GPA typically involves small to medium-sized blood vessels in the respiratory tract and kidneys. It can cause respiratory problems, kidney damage, and other systemic symptoms.
4. Eosinophilic Granulomatosis with Polyangiitis (EGPA, formerly Churg-Strauss syndrome): EGPA often affects small to medium-sized blood vessels and is associated with elevated levels of eosinophils in the blood. It can affect the respiratory system, skin, nerves, and other organs.
5. Microscopic Polyangiitis (MPA): MPA primarily affects small blood vessels in the kidneys, lungs, and skin. It can lead to glomerulonephritis (kidney inflammation) and pulmonary hemorrhage.
6. Polyarteritis Nodosa (PAN): PAN typically affects medium to large-sized arteries and can lead to damage in various organs, including the skin, nerves, and gastrointestinal tract.
The exact cause of systemic vasculitis is not well understood, but it is generally believed to result from an abnormal immune response. Genetic and environmental factors may also play a role in the development of these conditions.
Diagnosis of systemic vasculitis often involves a combination of clinical evaluation, blood tests to detect inflammation markers and specific antibodies, imaging studies, and sometimes a biopsy of affected tissue. Early diagnosis and treatment are crucial to manage symptoms and prevent complications.
Treatment typically involves medications to suppress the immune system’s overactive response and reduce inflammation. The choice of treatment depends on the specific type of vasculitis and its severity. In some cases, long-term or even lifelong treatment may be necessary to control the disease and prevent flare-ups. Healthcare providers with expertise in rheumatology or immunology usually manage the care of individuals with systemic vasculitis.
RAJESH KUMAR AGGARWAL5 October 2023Dr. Himanshu Aggarwal is very humble and experience doctor in his field.Vinay Gupta4 October 2023Really an eminent doctor..His diagnosis helped me a lot, ..May God bless him...Ritik Singh.22 September 2023Dr. Himanshu Aggarwal (Rhemutologist)is good in nature. he gives enough time to patient to satisfaction, and clear all the quarries of the patient.Vishesh Singla22 September 2023I visited Dr himanshu aggarwal for my relative's arthritis nd within few weeks she start getting relief.. Thanks to himYogendra Singh13 September 2023डॉक्टर हिमांशु अग्रवाल जी मैक्स अस्पताल में जो हड्डी ज्वाइंट का इलाज करते हैं मेरा भी इलाज किया और मैं अपने को शत प्रतिशत ठीक महसूस करता हूं डाक्टर साहब जी को कोटि कोटि प्रणाम करता हूंJai Rawat29 August 2023Excellent Doctor, Great humanitarian Dr Himanshu Aggarwal listens very patiently & gives sufficient time to say his problem.He studies the patient and disease meticulously.He is very cheerful and gentle in his behavior.I think he is best rheumatologist in Dehi,Ghaziabad NCR.Hikmat Bahadur Aidei13 August 2023He is god for us.Ran Singh Chauhan10 August 2023First of Thankyou very very much Dr for given to valuable tratement to my disease ankylosing spondylitis.. I suffering from last five years ankylosing spondylitis and I started tratement to dr last six months before. After tratement my body pain or stiffness are ok and I sleep on bed easily.... .Yashas Bhatt27 July 2023Dr Himanshu is very humble, Knowledgable and understanding doctor. I have went to him for my mothers treatment. At first when my mother went for her check up we thought it's gonna take a lot of time for my mother to get better as she was unable to walk and was on wheel chair, but when she got consultation from him and he made us understand what's the cause of it and started my mothers treatment and within a few days my mother started getting better and now she is able to walk also. Excellent doctor for Arthritis related diseases.Saurabh Agrawal21 July 2023I met Dr Aggarwal with my mother in law on 12th Aug 2022 on Friday. Her age is 78 years and 4 months and she is suffering from Rheumatoid Arthritis, Ankylosing Spondylitis , Asthma and Diabeties. But we went to Dr Aggarwal for the treatment of RA and AS. Personality and Characteristics: Dr is very young, smart, dynamic, humble, polite and very down to earth. Listening : His listen, every single problem shared by me and my Mother in law. She gave ample amount of time and understand the history. Diagnosed: He had seen all the past 5 years reports, Prescriptions which we were carrying at least for 10-15 mins . He did not ask us to do all the tests again those my last Dr conducted just 15 days back. He considered all tests and reports. Treatment: He had given some injections initially with oral tabs and ask to come weekly then by monthly after wards once it is required. Initial first or second week the pain and swelling of my mother in law had declined like anything. My in law started moving with the help of stick before that she was not able to move from the bed. This is the first line of faith developed in my and in law mind . You dnt believe it now almost 1 year completed and my mother in law is walking without stick easily. Her medications are limited and orally only. I again insist you to meet the Dr Aggarwal if you are or near one or dear one suffering from joint pain. Thank you Dr Aggarwal!